If the drive has not been tried out on another machine, that's the first thing to try. If two different machines don't recognize it, the drive is fried.
USB thumb drives are notorious for failing "out of nowhere" at almost every age. Many go for years and years, but eventually up and die. That's the most likely scenario here, but there are simple steps, like seeing if any computer recognizes the drive, that can help to rule in/out actual device failure.
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Brian - Windows 10, 64-Bit, Version 21H2, Build 19044
Here is a test to find out whether your mission in life is complete. If you’re alive, it isn’t.
~ Lauren Bacall