I took possession of a Logitech K 380 a few weeks ago.

Whilst It is not this keyboard that you are looking at but found the following which might possibly apply across Logitech keyboards.

1. For good screenreader compliance you need to change the function keys from hardware   media etc to normal Function keys.
2.  The options software you download from Logitech to achieve this – which I think is used for all Logitech keyboards is very screenreader unfriendly and realistically you need sighted help to install and use it.
3. My keyboard has no application key. I have to use shift F10 but  occasionally  it does not respond. In these circumstances though using FN F6 will bring up the context menu on my Logitech.
4. If you change the function keys to normal you gain an insert key. By default this is the volume down  key on my keyboard.

David Griffith

Sent from Mail for Windows 10