I was using JAWS 2020 with Slack. Slack was putting JAWS into application mode regularly, and I'd press the + key to get back into virtual PC mode. This allowed me to navigate by regions fairly well. I've installed JAWS 2021 and now notice I can't get out of application mode in Slack. The same is true for JAWS 2020. The only major change I'm aware of is that I installed JAWS 2021.